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The radiosensitivity of the human oocyte

By on April 6, 2011 in FertilityPreservation

This study advances the authors long interest in the subject of fertility estimation after radiation therapy.  Fertility preservation matters when we think about successful cancer treatment and more recently, for normal women who are not ready for pregnancy at an older maternal age. The authors use the best available mathematical models of oocyte depletion in [...]

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AMH as a Predictor of Natural Fertility

By on April 5, 2011 in FertilityPreservation, Infertility, Outcomes

Antimüllerian Hormone as a Predictor of Natural Fecundability in Women Aged 30–42 Years This small study is valuable because it tracked normal women who were beginning their efforts to conceive. So many studies that are retrospective, leave out the women who fail and are therefore not identified. The study included only 100 women, therefore they [...]

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Genetic Markers Predict Menopause

By on October 24, 2010 in FertilityPreservation, Infertility

Researchers at the University of Exeter in England identified 4 genetic markers for early menopause. (Link to scientific paper – open access download.) The following abstract from their publication in the Journal “Human Molecular Genetics” suggests that while these markers predict early menopause, the strength of their prediction is low. ABSTRACT: Women become infertile approximately [...]

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Reimplantation of cryopreserved ovarian tissue from patients with leukemia is potentially unsafe

By on August 20, 2010 in FertilityPreservation

Ovarian cryopreservation is a technique for fertility preservation of cancer patients. About 13 live births resulted from this technique since about 1995 when the experimental technique began after research in sheep. This study involved the ovaries from 18 females with a mean age of 14.5 years for acute lymphoblastic leukemia (ALL) and 24.7 years for [...]

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Researchers develop AMH model to predict menopause with 3-4 months accuracy. Preliminary but interesting.

By on June 27, 2010 in ART/IVF, Featured, FertilityPreservation, Infertility, Outcomes

Iranian researchers studied the AMH level of 266 women, aged 20-49, and developed a statistical model to predict menopause. They presented this data at the ESHRE meeting in Rome. Click here for the press release. The authors acknowledge that they need more data to confirm their findings. Other experts suggest that AMH has not been [...]

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Emergency IVF for Cancer Yields Similar Results as IVF for Infertility

By on May 27, 2010 in ART/IVF, FertilityPreservation

The study compared the outcomes of emergency IVF for cancer to IVF for tubal factor infertility. They had 22 women in each group and the outcome measures were similar between the two groups. Also, the emergency IVF did not delay the cancer treatment much if any. Two of the cancer patents (9%) had no embryos [...]

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Rates of Postcancer Parenthood — J Clin Oncol

By on May 5, 2010 in FertilityPreservation, Infertility, Outcomes

Although fertility-sparing treatment is allowing more patients to have children after cancer, the gains are minimal compared with the elevated rates of childlessness among cancer survivors. As Cvancarova et al point out, the need for more effective fertility preservation for girls and young women is particularly pressing. Even with the availability of sperm banking for [...]

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Embryologist freezing embryos eggs sperm for storage in laboratory

Why I Froze my Eggs

By on April 24, 2010 in ART/IVF, FertilityPreservation, Infertility

Egg freezing is a controversial issue in reproductive medicine because only relatively recently have fertility centers been able to reliably freeze eggs unlike sperm, which we have been freezing for decades. Egg freezing may find usefulness for women about to undergo cancer treatments that would otherwise destroy all their eggs. The technique may also be [...]

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What About Egg Freezing?

By on April 24, 2010 in ART/IVF, FertilityPreservation, Surveys

Here is a survey poll to get your thoughts on elective egg freezing. Egg Freezing is a “new” technique to store unfertilized eggs for future fertility. Banking gametes (eggs or sperm) is not new in that we have frozen sperm for decades and eggs for many years. What is new is that egg freezing has [...]

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AMH Levels May Predict Chemotherapy-Related Egg Loss

By on April 19, 2010 in FertilityPreservation, Outcomes

Cancer chemotherapy can lead to early menopause and sterility. The specific chemo drugs and dose determine the risk of sterility but our ability to accurately predict the affect is limited. AMH is believed to reflect the total number of remaining eggs in the ovaries. This study suggests that AMH levels may provide a better method [...]

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