Tag Archives | IVF

Embryo Cohort Size Does Not Affect Rate of Normal Embryos

The study showed that the size of the embryo cohort does not affect the rate of normal embryos identified by PGD. The authors used array CGH to evaluate embryos on day 3 and day 5. The study was retrospective using data from a PGD reference lab. They studiedĀ 7753 embryos from 990 patients. Embryo Cohort Findings [...]

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Metformin reduces OHSS risk in PCO patients during IVF cycles

Metformin reduces risk of OHSS in patients with PCO during gonadotropin-stimulated IVF cycles – a randomized controlled trial. (Article in-press at Fertility and Sterility Journal) Why is this study important? OHSS is a potentially serious complication of COH (controlled ovarian hyperstimulation) but it most commonly presents after IVF stimulation because we try to stimulate more [...]

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Individualized Ovarian Stimulation Best

I have come to believe that one of the key factors that differentiates IVF outcomes is individualization and management of ovarian stimulation. The reviews and opinions expressed are mine alone and are personal to me and do not necessarily reflect or represent the views or opinions of my employer or statements of purported fact.

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Frozen Blast Transfer Reduces Ectopic Pregnancy Risk

Japanese researchers explored a national database to determine whether thawed single-blast embryo transfer in natural cycles would reduce the risk of an ectopic pregnancy. The reviews and opinions expressed are mine alone and are personal to me and do not necessarily reflect or represent the views or opinions of my employer or statements of purported [...]

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Frozen-Thawed Donor Eggs Work as Well as Fresh Eggs

A prospective study demonstrates that frozen vitrified donor eggs yield the same outcome as fresh donor eggs in this nice prospective study. Egg freezing has been long in the development because the egg (oocyte) is particularly sensitive to the freezing-thawing process. The reviews and opinions expressed are mine alone and are personal to me and [...]

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Cryotank with Cryotube

Effect of Age and Embryo Quality on Outcomes in Frozen-Thawed Single Embryo Transfers

Take Home Message on Embryo Quality and Frozen Transfer Cycles: Embryo quality (measured as morphology or shape) remains an important factor for selecting which embryo to transfer. Some clinics do not keep embryo quality information on their frozen embryos. Thus, they randomly transfer embryos in the frozen cycle and their success rates are not optimized [...]

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Paternal Age May Not Affect ART Outcomes

The effect of paternal age on assisted reproduction outcome Objective To summarize the current knowledge about the association between paternal age and assisted reproductive technology (ART) outcomes because most studies examine the effect of maternal age on ART outcomes. Design Systematic review of the literature Result(s) Conclusion(s) There is insufficient evidence to demonstrate an unfavorable [...]

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IVF Embryologist Incubator

Deep phenotyping to predict live birth outcomes in IVF

Deep phenotyping to predict live birth outcomes in IVF – the authors suggest that their mathematical model is 100x more accurate than using age to predict IVF outcomes. The authors took data from previous IVF cycles at Stanford and developed a model using complicated statistical tests. They tested the model on IVF cycles from a [...]

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Telomere Length Measures Embryo Health

Genetic technologies invade every aspect of medicine. Here we find another example of a technology that could significantly assist us in identifying the embryo that will make a baby. The authors suggest measuring telomere length may be a measure of embryo health. If so, then this test may be a very valuable tool to access [...]

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Australia’s first IVF baby turns 30 and wants everyone to know that IVF-lings are normal

Australia’s First IVF Baby Turns 30: she wants IVF to be taught as normal process in health education. She says that IVF-lings want to let everyone else know that they are normal people. Click her for the full story. This is a nice story from the perspective of an IVF conceived woman. The reviews and [...]

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