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Embryo Cohort Size Does Not Affect Rate of Normal Embryos

By on May 20, 2012 in ART/IVF, Infertility, PGD

The study showed that the size of the embryo cohort does not affect the rate of normal embryos identified by PGD. The authors used array CGH to evaluate embryos on day 3 and day 5. The study was retrospective using data from a PGD reference lab. They studied 7753 embryos from 990 patients. Embryo Cohort Findings [...]

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Seattle Mom One of Nation’s First to Benefit From New Anti-Miscarriage Technology

By on July 21, 2010 in ART/IVF, Featured, PGD

One of our patients benefited from the use of PGD with array-CGH for recurrent pregnancy loss. We have been very pleased with the technology which now allows us to determine the number of copies for each of the 24 possible chromosomes. Please read the media posting. Recurrent Pregnancy Loss is frequently caused by a genetically [...]

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The right not to know and preimplantation genetic diagnosis for Huntington’s disease — Journal of Medical Ethics

By on May 13, 2010 in ART/IVF, Outcomes, PGD

Huntington’s Disease is a debilitating fatal autosomal dominant disease that has its onset in mid-life after childbearing is usually complete. Thus, some people do not want to know if they carry the gene because they then know their medical fate. The Genetics & IVF Institute developed a non-disclosing PGD method to prevent these couples from [...]

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RBM Online – Real-time PCR method for rapid sexing of human preimplantation embryos

By on May 5, 2010 in ART/IVF, Gender Selection, PGD

In this blinded prospective study, the authors showed that rapid and reliable real-time PCR-based gender identification of preimplantation human embryos using a single blastomere can be performed within about 4 h after biopsy. We often want more information than this study determined but there are situations where this technique would be useful. The most obvious [...]

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PGD is Cost Effective for Cystic Fibrosis

By on May 1, 2010 in ART/IVF, Outcomes, PGD

This study demonstrates that it is cost effective to use IVF with PGD to prevent the birth of a child with cystic fibrosis (CF). The cost benefit evaluates the medical costs not the human costs which are significant. Importantly, the benefit extends to at least a mother’s age of 40. IVF/PGD comes with what appears [...]

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PGD with Array-CGH Pregnancies

By on April 23, 2010 in PGD

Our center participated to produce the results of this research presentation. The data were presented by Dr Munne at the Pacific Coast Reproductive Society on Friday April 16, 2010. The data suggests that array-CGH provided results of all 24 chromosomes with no greater error rate than the current technique called FISH. The success and implantation [...]

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PGD for Gender Selection in the USA

By on April 19, 2010 in Gender Selection, PGD

The authors review a large series of PGD procedures for gender selection. They did not find evidence of a particular preference for choosing one sex over another or for couples to produce one sex over another. They found that over 50% of couple who did not get any embryos of the desired sex still transferred [...]

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